Details About: Farmapram Alprazolam
Farmapram Alprazolam belongs to the group of anxiolytics. It is prescribed for neurosis and psychopathy, which is accompanied by an anxious, restless state. The drug is effective for depression, including if it is caused by somatic diseases. For the treatment of patients with alcoholism and drug addiction, the drug is prescribed in case of diagnosis of panic disorder or abstinence syndrome.
Composition of Farmapram (Alpazolam) 2mg
The main component of the drug alprazolam is a benzodiazepine derivative. The active substance is insoluble in water and poorly soluble in alcohol. It is available in 0.25 mg, 0.5 mg, 1 mg, and 2 mg tablets.
Farmapram Alprazolam binds to benzodiazepine and GABAergic receptors. It affects the limbic system, thalamus, hypothalamus, polysympathetic spinal receptors, causing their inhibition. It has anxiolytic, myorelaxant, central, and sedative effects on the body.
After internal administration complete absorption occurs after 1-2 hours. Up to 80% of the substance is bound to blood plasma proteins. It penetrates through the BBB, placental barrier, and breast milk. Metabolism in the liver takes 16 hours. Excretion of the substance occurs through the kidneys. Cumulation occurs if repeated intake is less than 8-10 hours apart.
Administration and dosage
Farmapram Alprazolam 2mg is taken orally only. The dosage is determined individually, depending on the course of the disease, and tolerance of the components. Therapy begins with a minimum dose of 0.25 to 0.5 mg, which the patient takes 3 times a day. If the drug is well tolerated every 3 – 4 days, the dose can be increased. The maximum allowable value is 3 – 4 mg.
Contraindications and peculiarities of use
– Individual intolerance to the main or auxiliary components.
– Acute attack of glaucoma.
– Disorders of liver and kidney function.
– Myasthenia gravis.
– Period of pregnancy and lactation.
– Age of patients under 18 years old.
– Liver damage in alcohol dependence.
– Adverse reactions and overdose.
The main adverse reactions include impaired motor and mental reactions, which are manifested in a wobbly gait, drowsy state, and dizziness. Gastrointestinal disorders are possible – constipation and nausea. Adverse reactions also include dysmenorrhea and itching on the skin. Paradoxical phenomena are manifested by aggressive reactions, anxiety, agitation, and hallucinations. With constant intake, an addictive behavior occurs. Withdrawal syndrome occurs if treatment is stopped abruptly.
Farmapram Alprazolam should not be combined with alcohol, neuroleptics, hypnotics, and narcotic drugs because of their increased effect. May affect reactions while driving vehicles. Discontinue use if paradoxical reactions occur.
Overdose may lead to CNS depression, coma, ataxia, and decreased reflexes. First aid should cause vomiting and gastric lavage. Under hypotension, norepinephrine is administered. The antidote to the drug is flumazenil. It may be administered only under hospital conditions.
How to use alprazolam oral
See also Warning section.
Read the Medication Guide provided by your pharmacist before you start taking alprazolam and each time you get a refill. If you have any questions, ask your doctor or pharmacist.
Take this medication by mouth as directed by your doctor, usually once daily in the morning. Do not take with a high-fat meal because doing so can increase the risk of side effects. Swallow the tablets whole. Do not crush or chew the tablets. Doing so can release all of the drug at once, increasing the risk of side effects. Dosage is based on your medical condition, age, and response to treatment. Your dose may be gradually increased until the drug starts working well. Follow your doctor’s instructions closely to reduce the risk of side effects.
Though it helps many people, this medication may sometimes cause addiction. This risk may be higher if you have a substance use disorder (such as overuse of or addiction to drugs/alcohol). Take this medication exactly as prescribed to lower the risk of addiction. Ask your doctor or pharmacist for more details.
When this medication is used for a long time, it may not work as well. Talk with your doctor if this medication stops working well.
Tell your doctor if your condition lasts or gets worse.